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A cancer drugmaker just failed a key trial and its stock is crashing (INCY, MRK)

Cancer drugmaker Incyte said on Friday that a key trial combining its cancer immunotherapy drug with a blockbuster drug from Merck failed in a late-stage trial.

  • Cancer drugmaker
  • Incyte's stock was down as much as 22% before markets opened on Friday morning, while Merck's was down a little more than 1%.
  • Cancer immunotherapy works by harnessing the body's immune system to treat cancer.
  • The trial was looking to see if combining two drugs — Merck's PD1 checkpoint inhibitor and Incyte's IDO1 inhibitor — that both essentially take the brake off the immune system to go after the cancer cells in people with metastatic melanoma could work even better than Merck's drug alone.

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