"I know that we've said that you cannot say anything about it ... but they didn't say anything about body language, so blink if you're running for president," Michaelson said with a grin.
He added: "I think I saw a blink."
Harris was inside the Senate building during the interview that aired Friday night. Per Senate rules , she could not openly discuss any potential campaign matters. So, she laughed off Michaelson's inquiry instead.
"I'm going to ... just keep my eyes open and not even blink," Harris said.
Harris joked about it on ABC's "The View" earlier in January, saying "I'm pleased to announce on 'The View' that I'm not ready to make my announcement,"
"I'm very tempted, but I'm not yet ready," she said.
Harris, an Indian American and a first-term senator, has exploded in popularity among Democrats in recent months, particularly after scrutinizing Trump's immigration policies and political nominees, namely Justice Brett Kavanaugh.
The Democrat made headlines for her intense line of questioning during Kavanaugh's confirmation hearing to the Supreme Court and demanded the FBI to thoroughly investigate the sexual-misconduct allegations his accuser, Christine Blasey Ford, leveled against him.
Prior to becoming a senator, Harris served as California's attorney general as well as the district attorney of San Francisco.
Watch a clip from Harris' interview here
SEE ALSO: Stephen Colbert got Kamala Harris to give the strongest hint yet that she may run for president in 2020