The project is financed by a loan facility from the Brazillian government and construction is being done by a Brazilian company Queiroz Galvao.
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The interchange is expected to reduce considerable traffic on the Accra-Cape Coast road. Residents living beyond the toll booth at Tuba and into Kasoa have had to endure stressful travels on the road.
Related: Parts of N1 closed to traffic
The project is a 270-metre interchange with two overpasses on the main Kasoa-Winneba Road, the 33-kilometre Kasoa-Obom-Amasaman road and 20 kilometres of road in the Ga South Municipality and Kasoa. Work began in December 2014.
Urban areas that will benefit from the 95-Kilometre asphalt roads included Cape Coast, Winneba, Elmina, Mankessim, and Agona Swedru.
President Mahama will also commission Elmina Bridge and Fish Processing Factory and the Kotokuraba Market.