Kane, who came on as a substitute late in Tottenham's 3-1 victory at Chelsea last week, has scored eight goals in his past four games against struggling Stoke.
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Kane back in Tottenham starting line-up
Harry Kane was back in the Tottenham starting team on Saturday for the first time since injuring his ankle a month ago.
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Danny Rose, Victor Wanyama and Serge Aurier were also brought into the Spurs team.
Spurs boss Mauricio Pochettino on Friday urged his side to keep their focus against relegation-threatened Stoke as they seek to nail down a Champions League place.
The club's first win at Stamford Bridge since 1990 left fourth-placed Spurs eight points clear of Antonio Conte's side.
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