In a letter to all Regional Health Directors, Medical Superintendents, Polyclinic In-Charges, Metro, Municipal and District Directors of Health Service in the region, the GHS said the move "contravenes government policy directive which gives approval to the wearing of Hijab."
"Kindly ensure strict adherence to this directive by all staff and managers concern," the statement concluded.
The GHS directive comes after a student nurse was refused work at the Ridge Hospital for not agreeing to remove her Hijab when her other colleagues had agreed to.
The development has sparked baseless claims of Islamophobia in Ghana on some social media platforms.
Activists on Twitter say the decision by the Ridge Hospital management to refuse the Muslim nurse work for not removing her Hijab amounts to Islamophobia.
"The number of people denying Islamophobia while describing instances of it really has me baffled. Is it that the word scares you or something?, a Twitter user said.
Another noted: "A woman was asked to take off her hijab in a public institution. That is oppressive, outrageous and unacceptable. She isn't the first to be bullied that way and won't be the last. Let's stop pretending we all live in harmony and address our Islamophobia problem."
Others believe it is a reach to such there is Islamophobia in Ghana.
"Perhaps the use of the word “Islamophobia” is a reach but there’s definitely some bias against Muslims. Don’t some of our churches preach against Islam all the time? If you’re asked about your perception of Islam off twitter, you’ll have a lot to say. Relax lol," a user said.
Another also said: "Islamophobia? No! A strong word. Maybe discrimination sometimes. I remember my first year in Uni there was this lecturer who referred to every female in the class who had her hair covered as a ‘Boko Haram’ girl or a terrorist."