Alhassan, Elvis Kyei Baffour's brace and Abass Nuhu goal ensured Liberty picked up their first win at the Carl Reindorf Park after the Club Licensing gave them clearance to use the Park.
The visitors netted through Alfred Opoku and Yahaya Mohammed but a double each from Alhassan Mubarak and Elvis Kyei Baffour, as well as a goal from Abass Nuhu, won all three points for the Scientific Soccer Lads.
At Akoon Park in Tarkwa, Medeama succumbed to a 2-1 home defeat to 10th-placed Elmina Sharks who had Mustapha Alhaji and Bernard Boateng to thank for a comeback victory. The visitors scored the first goal through Prince Opoku Agyemang.
Full results on Sunday
Kotoko 0-0 AshantiGold
Dwarfs 2-1 Karela
Hearts of Oak 3-2 Bechem United
Liberty Professionals 5-2 Aduana Stars
Medeama 1-2 Elmina Sharks
WAFA 0-0 Dreams