The accident occurred at Osubetor Community on Koforidua to Mamfe road Wednesday, September 30, 2020, afternoon.
The students made up of three males and a female were onboard a Nissan Versa with registration number GE 6248-19 heading to Koforidua but the car veered off the road and crashed into trees at the roadside.
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The driver was reportedly sleeping according to an eyewitness.
One of the male students suffered a deep cut on the forehead while others were seen with minor injuries. The driver escaped unhurt.
They were rescued and rushed to the hospital by a Police Car heading to Koforidua.
The Eastern Regional Police MTTD is to establish the exact school the students attend.