A Stephen Nyarko's header in the 39th minute was enough to give the Porcupines Warriors a well deserved victory.
The attacking midfielder pounced into the goal area to connect his head to Kwame Boahene's cross beyond the reach of ASEC goalie, Sylla Mamadou.
The match was part of the commemoration of the 20th Anniversary celebration of Asantehene Otumfuo Osei Tutu II who ascended the throne 20 years ago.
Asante Kotoko and ASEC Mimosa have together annexed 81 major trophies in history and have contributed immensely to the development of football and unity in Africa not forgetting the great football talents they have produced in time past.