Mkhitaryan, a close-season signing from Borussia Dortmund, has shaken off a knock sustained on international duty with Armenia to line-up alongside Lingard and Wayne Rooney behind striker Zlatan Ibrahimovic, with Juan Mata and Anthony Martial dropping to the bench.

As expected, City boss Pep Guardiola hands a debut to Claudio Bravo following the goalkeeper's arrival from Barcelona, while Kelechi Iheanacho is a like-for-like replacement for suspended top scorer Sergio Aguero in attack.

Leroy Sane could also make his City bow after returning to fitness from a hamstring injury to take a place on the bench, although Mkhitaryan's former Dortmund colleague Ilkay Gundogan (knee) must continue his wait to be involved in the Premier League.