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According to initial reports, 20 are in critical condition and are receiving treatment at the Winneba Specialist and Trauma Hospital.
The crash happened on Tuesday, May 30, 2023, around 4:30 am.
According to eyewitnesses, the accident occurred after a head-on collision between a petrol tanker and a bus.
The bus was travelling from Abidjan to Buduburam while the tanker was filled with petrol, travelling from Accra heading towards Takoradi.
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The two vehicles collided head-on when the bus entered the lane of the tanker in the on-coming direction.
The 16 deceased passengers perished on the spot.
The bodies haven been deposited at the morgue of the Winneba Specialist and Trauma Hospital.